Joshua Garrett, Assistant Professor of Biology

329 Johnstone Science Center
garrettj@hartwick.edu
607-431-4732

Areas of expertise:
anatomy and physiology, cardiovascular physiology, endothelial barrier function, angiogenesis
Education:
Ph.D., Albany Medical College

Recent courses taught:

  • BIOL 206 Human Anatomy and Physiology I
  • BIOL 320 Human Anatomy and Physiology II

Distinctions (awards, fellowships, and grants):

  • 2015 Albany Medical College Leonard Procita Award for Excellence in Teaching
  • 2013 Albany Medical College Dean’s Award for Excellence in Research
  • 2010 Albany College of Pharmacy and Health Sciences Senior Researcher Award

Selected publications:

Peer-Reviewed publications:

Garrett JP, Lowery AM, Adam AP, Kowalczyk AP, Vincent PA. The role of the p120∙VE-Cadherin interaction in regulating endothelial barrier function. Mol Biol Cell. 2017 Jan 1;28(1):85-97.

Garrett JP, Lowery AM, Kowalczyk AP, Vincent PA. The binding of p120-catenin ARM domains to VE-Cadherin regulates endothelial barrier function independently of VE-Cadherin endocytosis. In preparation.

Spinelli AM, González-Cobos JC, Zhang X, Motiani RK, Rowan S, Zhang W, Garrett J, Vincent PA, Matrougui K, Singer HA, Trebak M. Airway smooth muscle STIM1 and Orai1 are upregulated in asthmatic mice and mediate PDGF-activated SOCE, CRAC currents, proliferation, and migration. Pflugers Arch. 2012 Nov;464(5):481-92·

Alsaffar H, Martino N, Garrett JP, Adam AP. IL-6 promotes a sustained loss of endothelial barrier function via JAK-mediated STAT3 phosphorylation and de novo protein synthesis. Am J Pathol. Under review.

Talks

Garrett JP, 2016. p120-catenin regulates endothelial barrier function by preventing Vascular Endothelial-Cadherin tyrosine phosphorylation. Research Seminar Series. Albany College of Pharmacy and Health Sciences, Albany, NY

Garrett JP, Lowery AM, Kowalczyk AP, Vincent PA. Expression of an endocytic-defective VE-cadherin mutant cannot restore cell-cell-adhesion in the absence of p120 in the endothelium. Oral presentation delivered at Experimental Biology Conference, Boston, MA, April 2013

Posters

Garrett JP, Lowery AM, Adam AP, Vincent PA. The Role of the p120-ARM Domains in the Regulation of Endothelial Barrier Function. Presented at Gordon Research Conference “Cell Contact & Adhesion”, Andover, NH, July 2017.

Garrett JP, Lowery AM, Adam AP, Vincent PA. The binding of p120-catenin ARM domains to VE-Cadherin regulates endothelial barrier function independently of VE-Cadherin endocytosis. Poster presentation delivered at International Vascular Biology Meeting. Boston, MA, Nov. 2016.

Garrett JP, Lowery AM, Adam AP, Kowalczyk AP, Vincent PA. VE-Cadherin/p120 interaction regulates endothelial barrier function independent of VE-Cadherin levels. Poster presentation delivered at North American Vascular Biology Organization Conference, Hyannis, MA, Oct. 2015.

Garrett JP, Lowery AM, Kowalczyk AP, Vincent PA. p120-catenin controls VE-Cadherin endocytosis to regulate angiogenic sprouting, but not endothelial barrier function. Presented at Gordon Research Conference “Cell Contact & Adhesion”, Andover, NH, July 2015.

Garrett JP, Lowery AM, Kowalczyk AP, Vincent PA. p120-catenin controls VE-Cadherin endocytosis to regulate angiogenic sprouting, but not endothelial barrier function. Presented at Gordon Research Seminar “Cell Contact & Adhesion”, Andover, NH, June 2015.

Garrett JP, Lowery AM, Adam AP, Vincent PA. Depletion of p120 catenin produces differential angiogenic sprouting in HDMECs and HUVECs. Poster presentation delivered at North American Vascular Biology Organization Conference, Hyannis, MA, October 2013.

College services and professional affiliations:

  • Member, American Physiological Society
  • Member, North American Vascular Biology Organization
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